Sequential embryo transfer is a medical procedure that involves the transfer of two sets of developing embryos into the mother’s uterus at different phases of her menstrual cycle. SET is one of the most popular procedures when it comes to IVF. After becoming a trend worldwide, SET has made its mark in the Indian market as well.
When it comes to In-Vitro Fertilization, Sequential Embryo Transfer is among the most common and most popular techniques. In this process, two partially developed embryos prepared in a laboratory are transferred into the uterus of the mother, on day 2-3 and 5-6 of her menstrual cycle. This technique ensures the implantation of the best-developed embryo in the mother’s womb, resulting in better outcomes. Along with this, other factors also affect the success of the sequential embryo transfer procedure. The patients are advised to maintain a healthy diet, stay physically active, and take natural vitamin supplements.
Initially, two sets of laboratory-developed embryos are transferred to the mother's uterus on days 2-3 and 5-6 in the same menstrual period.
The first set of embryos transferred comprises rapidly growing good quality embryos, which are transferred in the mother's womb after 2-3 days.
After the first set is transferred, a second set consisting of healthy and good quality embryos is transferred to the mother's womb after 5-6 days.
As the second set of embryos are deployed after 5-6 days of life, they are comparatively more mature than the first one, and eventually reach the blastocyst stage of embryo development.
As the second set of embryos is more developed, they find it easier to connect with the uterine wall and start releasing the cytokines, which helps replenish uterus and results in better implantation.