Treatment route is decided after taking into consideration the count, motility and morphology of sperms. When these parameters are marginally low, simple treatment options like Intra-Uterine Insemination (IUI) are found to be helpful. In extremely low parameter count, advanced treatment option like ICSI is opted for. While IMSI and PICSI are used for selection of morphologically normal sperms during ICSI.

Sperm production and maturation in the testes i.e., Spermatogenesis takes about 72 days. Hence, two to three months of medication is required to see the improvement in semen analysis report. If there is no improvement even after administration of medication, ICSI treatment option is chosen to achieve pregnancy. In these cases, the success rate is around 50-60% when other parameters are normal.

If a male follows a healthy diet, exercises regularly, refrains from smoking, alcohol, gutka and habit-forming drugs along with avoiding use of tight undergarments and reducing weight, the whole problem can be avoided to begin with.