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IMSI Treatment

IMSI: Purpose, Procedure & Results

What is Intra-Cytoplasmic Morphologically-Selected Sperm Injection (IMSI)?
IMSI has a high success rate of IVF overcoming male infertility. This is a preferred mode of treatment for patients suffering with Teratozoospermia (sperm with severely adverse morphology) which leads to failure of impregnation through IVF. This is one of the trusted ways of achieving good quality embryos.
When to opt for IMSI?

IMSI is a preferred course of treatment in following scenarios: –

What is the procedure for Successful IMSI?
This procedure is very similar to ICSI wherein the wife is first injected so that the follicles are well-developed. Oocytes are then extracted from these developed follicles and injected with husband’s spermatozoa. This spermatozoa is selected rather carefully. Spermatozoa is first magnified to 6600x to check for any morphological abnormalities. The single spermatozoa which is in good shape and health is then selected and injected into the oocyte and the resultant embryo is then implanted into the uterus.

IMSI gives the embryo a better chance of surviving and developing to the full-term of pregnancy.

Fast Facts:

This treatment is best suited to patients

With poor sperm

With few embryos developing to the blastocyst stage

With a higher level of DNA fragmentation in sperm

Doctor Speaks


Egg retrieval is the first step in IVF, where the mother’s eggs are extracted from her ovaries, after she takes hormone-inducing medications, to fertilize them in a lab with sperm. The resultant embryos are inserted back into the uterus for implantation.
Intrauterine insemination (IUI) is among the most frequently employed infertility treatments for couples who have been unable to conceive. While IUI benefits many couples, it is not always an assured remedy for all. Therefore one must be aware of why IUI fails and what should be done afterwards.

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