One of the most common reasons for IUI failure is poor sperm quality. In most cases, poorly motile sperms are not strong enough to reach the fallopian tubes and complete the process of fertilization. On the other hand, the timing of IUI plays a crucial role; that means if the sperm transfer is due within 12-24 hours of ovulation, the egg present in the fallopian tube will disintegrate.
Patients who have had two or more failed IUIs are more likely to consider IVF. Given the high success rates of IUI, several couples opt for three or more cycles before attempting IVF.
Fertility experts recommend three rounds of IUI before considering IVF for women under 35; however, this recommendation can go up to six in carefully selected cases. Given that age has a significant impact on fertility, this recommendation will likely be lower if you are over 35.
Fertilization occurs in the body through IUI, whereas during IVF, fertilization takes place in the lab. Generally, IUI may be the only treatment needed. But fertility specialists may suggest IVF if IUI does not work.
The insemination procedure is pretty quick and takes about 5-10 minutes. You don't need anesthesia as IUI is usually not painful, but some people may experience symptoms of mild cramping.
Bed rest for 10 and 20 min after intrauterine insemination has a positive effect on the pregnancy rates, but complete bed rest after IUI is not required.