Male Infertility and its Causes

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Infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8–12% of couples worldwide. Of all infertility cases, approximately 40–50% is due to “male factor” infertility and as many as 2% of all men will exhibit suboptimal sperm parameters.

It may be one or a combination of low sperm concentration, poor sperm motility, or abnormal morphology.

Causes of Male Infertility

More than 90% of male infertility cases are due to low sperm counts, poor sperm quality, or both. The remaining cases of male infertility can be caused by a range of conditions including anatomical problems, hormonal imbalances, and genetic defects.

Sperm Abnormalities

Sperm abnormalities are a critical factor in male infertility. These abnormalities include:

  • Low sperm count
  • Poor sperm motility (movement)
  • Abnormal sperm shape

Risk Factors

  • varicocele, an enlarged varicose vein in the spermatic cord that connects to the testicle
  • Aging, which can reduce sperm counts and motility and decrease the genetic quality of sperm
  • Sexually transmitted diseases, which can cause scarring in the male reproductive system or impair sperm function
  • Lifestyle factors such as smoking and substance abuse
  • Long-term or intensive exposure to certain types of chemicals, toxins, or medications

Diagnosis

In addition to a medical history and physical exam, specific tests for male infertility include:

  • Semen analysis to evaluate the quantity and quality of sperm
  • Blood tests to evaluate hormone levels
  • Imaging tests to look for structural problems
  • Genetic testing to identify sperm DNA fragmentation, chromosomal defects, or genetic diseases

Treatment

Treatment for male infertility should first address any underlying medical conditions that may be contributing to fertility problems. Drug therapy may be used to treat hormonal disorders. Surgery may be used to repair varicoceles and correct any obstructions in the reproductive tract.

If fertility issues remain unresolved, intracytoplasmic sperm injection (ICSI) is commonly used in combination with in vitro fertilization (IVF) to achieve pregnancy when male infertility is a factor. ICSI involves injecting a single sperm into an egg obtained through IVF. The fertilized egg is then implanted back into the woman. Pregnancy success rates depend on many different factors.

Dr.Narahari Malagaonkar

Fertility Consultant

 MD, DNB, FCPS, DFP ( Mumbai),

Fellowship in Reproductive Medicine (Singapore)

Contact@+919403932404,0253-2347721, E-Mail: drmalagaonkar@progenesisivf.com

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शुक्राणूंची क्वालिटी किंवा पुरुषांची फर्टिलिटी क्षमता कोणत्या घटकांवर अवलंबून असते?

महिलांचे स्त्रीबीज आणि पुरुषांचे शुक्राणू एकत्र आल्याने महिलेला गर्भधारणा होते. शुक्राणू शिवाय गर्भधारणा अशक्य आहे. अस्वस्थ शुक्राणुंमुळे गर्भधारणेत समस्या असल्यास आधुनिक IVF -ICSI / IMSI / PICSI सारख्या फर्टिलिटी उपचारांनी गर्भधारणा होऊ शकते. मात्र अन्य गंभीर समस्यांमध्ये पुरुषांचे शुक्राणू जेव्हा गर्भधारणेसाठी असमर्थ ठरतात, तेव्हा देखील डोनर स्पर्म च्या मदतीने गर्भधारणा होऊ शकते.